At the end of your morning and evening skincare routine, take a small pearl-sized amount on your fingertips and gently apply to areas where wrinkles are a concern, such as around the eyes and mouth. *If you use it in the morning, please use cosmetics with UV protection afterwards to protect the effects of the retinol. *Please refrain from using this product if you have previously had problems with products containing retinols or are prone to skin problems. *If using for the first time or if your skin is sensitive, we recommend gradually increasing the amount used, using it only at night every 2-3 days for the first 2 weeks, and then every night for the next 2 weeks. *When using in combination with other products containing retinol, avoid using multiple products at once and use each product one at a time, monitoring the condition. *Please observe the recommended number of times and amount used.